Studies on the Syntheses of 1, 4-Thiazine Derivatives. II
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چکیده
منابع مشابه
Benzylpiperazine derivatives. IV. Syntheses and cerebral vasodilating activities of 1-benzyl-4-diphenylmethylpiperazine derivatives.
A considerable body of literature exists on the biological activity of compounds containing the piperazine moiety. In the field of 1-benzyl-4-diphenylmethylpiperazines, antihistaminics,2-4) tranquillizers,5,6) and vasodilators7) have been reported. Some of them, such as buclizine (1), meclizine (2) and medibazine (3), have been used clinically. More recently, 1-diphenylmethyl-4-(4-hydroxybenzyl...
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The ultrasonic velocity, density and viscosity of some Schiff bases of 4-amino benzoic acid were measured in 1,4-dioxane and dimethylformamide at 308.15 K. Various acoustical properties such as isentropic compressibility (ks), Rao’s molar sound function (Rm), the Van der Waals constant (b), molar compressibility (W), inter molecular free len...
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The syntheses of tris(organostannyl)methanes HC(SnX n Ph(3-n))3 (1, n=0; 2, n=1, X=I; 3, n=1, X =F; 4, n=1, X=Cl; 5, n=1, X=OAc; 6, n=2, X=I; 7, n=2, X=Cl) and the organostannate complexes Et4N[HC(SnIPh2)3⋅F] (8), Ph4P[HC(SnClPh2)3⋅Cl] (9), and [Ph4P]2[HC(SnCl2Ph)3⋅2 Cl] (10) are reported. The compounds were characterized by 1H, 13C, 19F, and 119Sn NMR spectroscopy, IR spectroscopy, electrospra...
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Reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). Reaction of diazomethane with compound 3 yielded the ester 4. Compound 5 was prepared from the reaction of N, N'-dialkylethyl (or propyl) arnine with 4. Addition of hydrazine hydrate to compound 4a gave 2- (2- pyridyl) quinoline-4-carboxylic acid hydrazide (6). Reaction of l...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1957
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.77.4_352